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Translational biopharmaceutics scientist

Torres Vedras
Tecnimede Group
Anunciada dia 22 março
Descrição

Tecnimede Group is a 40 years Portuguese multinational company that wants to improve and preserve human life and health through the development, production and marketing of pharmaceutical products with a strong focus on quality and technological innovation. The group covers the entire life cycle of the medicinal products for human use with a strong investment in research and development.We are looking for aTranslational Biopharmaceutics Scientistto support the scientific translation of pharmaceutical design into predicted in vivo performance. This position sits within Pharmaceutical Development and will focus on building mechanistic understanding across in vitro, in vivo, and in silico data to inform development strategy. The role will work closely with Clinical, Regulatory, and CMC teams to ensure scientific alignment, without direct responsibility for clinical trial execution or operations.Key ResponsibilitiesTranslational & IVIVC Strategy Develop IVIVC/IVIVR frameworks linking formulation attributes toin vivobehavior Define clinically relevant dissolution and release methodologies Integrate CQAs with biopharmaceutic and pharmacokinetic rationale Contribute to PBPK and predictive modeling strategiesPreclinical & In Vivo Scientific Support Design, review and support pre-clinicalin vivostudy protocols Interpretin vitroandin vivodatasets to guide formulation and dose rationale Support translation of key findings into human exposure expectationsAdvanced & Complex Therapies Provide scientific input into protocol concepts for early human studies, including cell gene therapies Support dose justification and risk assessment from a CMC and translational science perspective Ensure CMC attributes are mechanistically aligned with anticipated clinical performance Contribute scientific sections to regulatory documentationWho are we looking for Advanced degree (MSc or PhD) in Pharmaceutical Sciences, Biopharmaceutics, Pharmacokinetics, Biomedical Sciences, or related discipline Strong understanding of IVIVC, PK/PD principles, and translational science Experience in pre-clinical in vivo study design and results interpretation Exposure to PBPK or similar modeling tools is valued Knowledge or experience in complex dosage forms (e.g., long-acting injectables, modified-release systems, peptide formulations), biologics, or advanced therapies (cell and gene therapy) is considered an advantage Ability to integrate multidisciplinary data into coherent development strategyWhy This Role Matters Tecnimede is reinforcing its innovative drug product development platform, with a focus on complex formulations, long-acting injectables, peptides, and advanced therapeutic modalities. As our portfolio evolves, we are strengthening the scientific integration between pharmaceutical technology, preclinical performance, and expected human outcomes.In compliance with the provisions of the GDPR and other legislation in force regarding the protection of personal data, the contracting company guarantees that the processing of your personal data is lawful, fair, transparent and limited to the purposes for which your data was collected.

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